NITRIC OXIDE IS THE KEY TO REGENERATIVE MEDICINE AND HUMAN OPTIMIZATION
As the title implies, nitric oxide is foundational for regenerative medicine therapies but also for allowing our own cells and tissues to repair and regenerate to prevent age related disease. Many of you have followed my hair transplant journey with great interest and enthusiasm. As many of you know, I also practice what I preach and so I thought I would share with you the science behind the practice. Obviously medicine is based on science but in the field of cosmetic, plastic and transplantation surgery, and other disciplines of medicine, the art of medicine is just as important in the final outcome.
I have been involved in nitric oxide research for more than 25 years. My first interest and first thought of a practical therapeutic application of the basic science we were discovering decades ago was in transplantation surgery. Not necessarily hair follicle transplants but in full organ transplants, such as heart, liver, kidney and lungs. There is a paradoxic phenomenon in the field of transplant surgery where the transplanted organs undergoes reperfusion injury.
To simplify, it is not necessarily the complete lack of blood supply to the organ from the time it is extracted from the donor, placed on ice, then transplanted into the recipient, but rather the injury occurs when the blood supply of the recipient is connected and begins to be perfused once fully transplanted. The reperfusion injury occurs because the mitochondria have a difficult time with the sudden surge of oxygen and they can create damaging oxygen radicals instead of cellular energy causing oxidative stress, inflammation and immune dysfunction that in many cases can lead to graft rejection.
The beauty of nitric oxide is that is protects the organs from reperfusion injury by recoupling the electron transport chain of the mitochondria and by scavenging any oxygen radicals produced during reperfusion. The key is to make sure the donor is replete in nitric oxide. Nitric oxide helps fully oxygenate the blood and tissue so the transplanted organ can properly function. For hair follicle transplant it is a bit different. The individual follicles are harvested from donor sites and then soaked in a regenerative solution of exosomes and then transplanted into recipient sites where there is thinning or no hair. There is no reconnection of blood supply to the transplanted follicles since they are served by small capillaries. Therefore for the follicle to become viable, blood supply must be established once follicle is transplanted.
This is where our oral nitric oxide lozenge and the topical nitric oxide come in. The lozenge opens up the small capillaries throughout the entire body to improve perfusion. The topical nitric oxide recruits capillaries to each transplanted follicle and induces angiogenesis or the formation of new blood vessels to the newly transplanted follicles. During my hair transplant procedure and journey, we were able to witness the actual science.
As shown above, Dr. Alan Bauman of Bauman Medical in Boca Raton, Florida, a pioneer and innovator in hair transplant surgery, extracted 4200 individual hair follicles and transplanted them to re-establish my hair line from 20 years ago and to fill in the crown where I was starting to lose hair. The individual follicles are shown in the first photo. The second photo was hours after the follicles were transplanted and after we applied our topical nitric oxide serum and platelet rich plasma to accelerate healing and success of the transplants. The last picture is 3 weeks out. Although perhaps not apparent, all of the transplanted follicles are growing in nicely, similar to a Chia pet just starting out. That was the first thought or analogy that came to mind.
Nitric oxide is not only important and foundational for transplants and the practice of medicine but it is absolutely essential for our own body to be able to regenerate and repair and replace dysfunctional cells. The 2003 Nature Medicine paper revealed that nitric oxide is required for mobilization of our own stem cells and for our body to repair. Without nitric oxide, our bodies cannot and will not heal leading to accelerated aging and rapid onset and progression of chronic disease.
It is exciting and gratifying discovering, watching, observing, innovating and witnessing the power of nitric oxide products that I have created. More gratifying though is witnessing the adoption and application of my nitric oxide products in medicine by leading physicians. They use my products because they work and they see their patients get better, recover more quickly and get better outcomes. The science is clear. Nitric oxide addresses all aspects of health and longevity by:
- Mobilizing our own stem cells. After taking my nitric oxide products, there are more stem cells in circulation to heal, repair and replace cells
- Improving mitochondrial function and inducing mitochondrial biogenesis so cells are able to produce more energy and produce less oxygen radicals.
- Activating telomerase enzyme and preventing our telomeres from getting shorter. Remember shorter telomeres, shorter life. Longer telomeres, longer life
If that is not enough, nitric oxide addresses the hallmarks of all age related chronic disease.
- Overcomes hypoxia/ischemia by dilating blood vessels, improving perfusion and fully oxygenating blood.
- Decreases inflammation
- Inhibits oxidatives stress
- Corrects immune dysfunction
If you want to improve your life, optimize your performance and become a better version of yourself, start to implement nitric oxide products into your daily routine. Just remember, most nitric oxide products on the market do not produce or provide any nitric oxide benefit. What makes us different is the nitric oxide molecule. If your body has lost the ability to produce nitric oxide, my N1o1 line of products do it for you.
Hair transplantation surgery is just the beginning as we move our technology through clinical trials. The earlier you start the better you will be. I want to extend a huge thank you to Dr. Alan Bauman and his entire team at Bauman Medical for the great care, hospitality and incredible results from the hair transplant. I highly recommend Bauman Medical for anyone dealing with hair loss issues or more importantly to visit them before you start to lose hair to implement preventative strategies.
You can find my nitric oxide products at www.n1o1.com Use coupon code NSB10 for a discount.
—
Dr. Nathan S. Bryan is a biochemist and physiologist that has more than 20 years of basic science and clinical research. His many seminal discoveries have resulted in dozens of issued U.S. and International patents. He is an international expert in nitric oxide and molecular medicine. Dr. Bryan is an innovator and successful entrepreneur who product technology is responsible for hundreds of millions of dollars in revenue worldwide. This content is not intended to replace medical advice from a physician.
Instagram @drnathansbryan
Twitter @drnitric
LinkedIn @drnathansbryan
www.drnathansbryan.com
https://www.youtube.com/@DrNathanSBryanNitricOxide
www.N1o1.com
www.bryantherapeutics.com